Tanning

Melanocortin Peptides: Melanotan I and II for Research, With the Safety Record First

This category holds research peptides that act on melanocortin receptors. Read the safety facts first, because these compounds carry a heavier record of harm than most peptides on our site. We test every batch by HPLC and mass spectrometry and attach a lot matched COA to each vial.

Products in This Category

Melanotan I targets one receptor and relates to afamelanotide, which holds FDA approval as Scenesse for a rare light sensitivity disorder. Melanotan II acts on several receptors, causes stronger effects, and has no approval anywhere. PT-141 descends from Melanotan II and became the FDA approved drug Vyleesi.

How to Choose

Compound Receptor profile Approval status
Melanotan I Selective for pigment receptor Related drug approved for a rare disorder
Melanotan II Non selective None
PT-141 More selective for MC4R Approved as Vyleesi

Safety and Regulation

Published case reports link Melanotan II to changing moles, melanoma, priapism, kidney injury, and muscle damage. Case reports cannot prove cause, but the pattern led dermatologists to issue public warnings. Anyone with a personal or family history of melanoma, many moles, or high blood pressure should avoid these compounds. We do not publish self dosing numbers. We sell everything strictly as research compounds, not for human or veterinary use and not for tanning. Regulators in several countries have restricted or banned human supply.

Related Categories

See the Sleep and Growth Hormone category or the Anti Aging and Skin category.

FAQ

What is the difference between Melanotan I and II?

Melanotan I targets one receptor. Melanotan II hits several and has a heavier safety record.

Does Melanotan II cause skin cancer?

No study has proven it, but case reports link it to melanoma and mole changes.

How does PT-141 differ?

PT-141 is more selective and holds FDA approval as Vyleesi.